It's being report all over that Brad Pitt and Angelina Jolie are interested in playing Galt and Dagny in the adaption of Atlas Shrugged. (link, link) Also, in an important step making it more likely that the movie will actually be made, Lions Gate has acquired worldwide distrubtion rights for the movie. This is a fairly big deal given that Lions Gate is coming off the Crash Academy Award win and is about to hit it big again with Akeelah and the Bee. They have also had big successes with their horror films Saw and Saw II and of course Fahreneit 9/11 because Michael Moore is a scary).
I am not sure what I think about Pitt playing Galt. But that's also an impossibly hard role to cast I've always liked Densel Washington). I see Pitt more as Rearden if they want to make Rearden younger (though one blog commentator has that role going to Billy Bob if Pitt gets Galt. I guess that means Johnny Lee Miller has to play Francisco).
Jolie as Dagny could definitely work. She's sexy, beautiful, tough, and intelligent.